In Vivo Study of Radioprotective Effect of NO-Synthase Inhibitors and Acetyl-L-Carnitine

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In vivo study of radioprotective effect of NO-synthase inhibitors and acetyl-L-carnitine.

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The Effect of Acetyl-L-Carnitine on Learning and Spatial Memory Deficit in Diabetic Rats

Background & Aims: Diabetes mellitus is a chronic metabolic disorder that in the long-term is accompanied with deficits in learning, memory, and cognitive skills. Due to the existing evidence regarding the anti-diabetic potential of acetyl-L-carnitine (ALC), the effect of its long-term administration on learning and spatial memory deficits was investigated in diabetic rats. Methods: In this exp...

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Acetyl-L-Carnitine Monograph

Introduction Acetyl-L-carnitine (ALC) is an ester of the trimethylated amino acid, L-carnitine, and is synthesized in the human brain, liver, and kidney by the enzyme ALC-transferase. Acetyl-L-carnitine facilitates the uptake of acetyl CoA into the mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. ALC, simila...

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ژورنال

عنوان ژورنال: Physiological Research

سال: 2013

ISSN: 1802-9973,0862-8408

DOI: 10.33549/physiolres.932541